Bruderer et al. (2015) recently published a paper detailing hyper reaction monitoring (HRM), a novel data-independent analysis (DIA) mass spectrometry (MS) technique. Built around SWATH-MS, another DIA approach that gives complete coverage of all fragment ions, the research team applied HRM to profile the proteome.1 Describing their technique as an improvement on shotgun proteomics, the team Read the rest of this article
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