Saturday, April 30, 2016
Friday, April 29, 2016
Thursday, April 28, 2016
The Food and Drugs Administration (FDA) has released a set of non-binding guidance notes on the subject of acrylamide in food (2016)1. This concise 37-page document summarizes current research, and leads with advice to food industry producers and food service industry workers on how to minimize human exposure through reducing levels of acrylamide in food. Read the rest of this article
from Amanda Maxwell – Accelerating Science http://ift.tt/1TfzOdb
Tuesday, April 26, 2016
Sariyar et al. (2015) discuss issues that arise with biobankers sharing and reusing biospecimens, especially when this takes place between different institutions and across borders.1 Referring to a one-day workshop held in July 2014 in Berlin, organized by the European Union–funded BioMedBridges project, they present a summary of issues arising with collaboration and present some online tools developed to help researchers navigate ethical, legal and Read the rest of this article
The post Tools to Guide Researchers on Ethically Sharing and Reusing Biospecimens appeared first on Accelerating Science.
from Amanda Maxwell – Accelerating Science http://ift.tt/24hiuvY
Monday, April 25, 2016
Research into obesity has recently turned to examining the gut microbiome for clues. Although nutrition and dietary habits are key determinants in both development of and treatment for obesity, researchers like Kolmeder et al. (2015) are now characterizing the potential role that the microbial population within the intestines plays.1 In a recent publication, the research team Read the rest of this article
from Amanda Maxwell – Accelerating Science http://ift.tt/1T8OMSg
Thursday, April 21, 2016
Sunday, April 17, 2016
Saturday, April 16, 2016
Friday, April 15, 2016
Thursday, April 14, 2016
Those who do not try will never succeed, though failure can often be a stepping stone to later success. However, for all biobanks the risk of failure from closure also includes problems inherent in the institution’s responsibility toward its biosamples. Stephens and Dimond (2015) explore this phenomenon in two papers, looking at events leading up to the closure of an anonymized disease-specific biobank in the United Kingdom and Read the rest of this article
from Amanda Maxwell – Accelerating Science http://ift.tt/1T67Oes
Tuesday, April 12, 2016
Foodborne infection results in transmission of many diseases with impacts on human health ranging from mild debility to death. Under the authority of the World Health Organization (WHO), the Foodborne Disease Burden Epidemiology Reference Group (FERG) has collated global estimates of foodborne disease (FDB), creating a report looking at the overall impact on human health Read the rest of this article
The post WHO Report: Global Estimates for Foodborne Disease Burden 2010 appeared first on Accelerating Science.
from Amanda Maxwell – Accelerating Science http://ift.tt/23AbA4B
Monday, April 11, 2016
Trung et al. (2014) describe a proteomics workflow that replaces in silico modeling with quantitative DNA-protein interactome data.1 The approach uses SILAC (stable isotope labeling of amino acids in culture) to identify proteins interacting with M8, a putative cis-regulatory element that may play a significant role in leukemia and lymphoma development. The M8 motif—TMTCGCGANR, where M Read the rest of this article
The post Identifying and Quantifying DNA-Protein Interactomes with Quantitative Proteomics appeared first on Accelerating Science.
from Amanda Maxwell – Accelerating Science http://ift.tt/23wWLQr
Sunday, April 10, 2016
Saturday, April 09, 2016
Friday, April 01, 2016
|happy roscoversary cake - Three Dog Bakery in Suter Brook|
We had only had Rosco for seven months when he went from four to three legs. The decision to amputate took almost a month and I will probably never forget the immense sadness that we all felt during that time. Bringing him home the night after his surgery was harrowing - here was our amazing hound starting life on three legs and in such distress as he got over the anaesthetic. We all had an extremely rough night; Rosco cried constantly while mr ebb and I took turns to sit with him.
But since that harrowing first night, Rosco has been an enormous inspiration. His attitude seems to be - OK, three legs ... but what's stopping us? He is keen for walks even though he doesn't go far. He is jumping up on the couch. He climbs stairs, steep banks, trails and the garden terracing.
We never expected to have to deal with so much so soon after adopting him. Making the decision to have his leg amputated knowing that he was already an infirm senior is not something we could take lightly. But his approach to life as a tripawd is infectious - now, just who rescued who?
Here's to many more.
Tweaking an experimental setup is one of the greatest joys—and frustrations—for research scientists. Optimizing methodologies to maximize data collection, increase efficiency and improve validity occupies many, many lab hours in the pursuit of pure science, and mass spectrometry-based proteomics analysis is no different. Strzelecka et al. (2015) recently reported validation of one of these tweaks, namely Read the rest of this article
The post More DMSO with Your Top 3 Label-Free Protein Quantitation? Yes, Please! appeared first on Accelerating Science.
from Amanda Maxwell – Accelerating Science http://ift.tt/1RPuzA1