Single Muscle Fiber Proteomics

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Skeletal or voluntary muscle tissue comprises fiber bundles made up of multi-nucleated single cells that fuse together following myoblast differentiation (reviewed here). Murgia et al. (2015) developed a mass spectrometry–based proteomics workflow that is capable of characterizing the proteome in single muscle fibers.1 Using specific markers within the different muscle types, they determined that analysis of Read the rest of this article

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