Death and the Maiden: Mummy Proteomics in Health and Disease

via Accelerating Science » Amanda Maxwell http://ift.tt/1NEHKnZ

Forensic examination of ancient remains is a fascinating subject, usually relying on DNA evidence to indicate the presence of pathogens; however, this presence alone does not necessarily indicate active disease or ascertain it as the cause of any observed pathology. To answer this problem, Corthals et al. (2012) turned to shotgun proteomic analysis to determine disease activity Read the rest of this article

The post Death and the Maiden: Mummy Proteomics in Health and Disease appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1XDT34u
via IFTTT

spt29oct15: dog as mindreader

He's pretty good at picking up on moods, emotions and so on, but right now I'm glad that he can't read my mind.
On Monday, Rosco is heading to the vets to have his left front leg amputated. The lump and the lameness have resolved radiographically into tumor - osteosarcoma most likely.
While I'm pretty much devastated, sweet Rosco is oblivious. The meds are holding the pain at bay as his left elbow slowly explodes - if we leave it much longer the pain will be too much or the bone will shatter.
I'm told that Tripawds do pretty well but I still think this sucks. Dog as mindreader knows that I'm worried about something and is looking after me. His turn coming soon.
Please send miracles.

daily snapshot: October 29, 2015 at 08:34AM

ooh and I guess #inktober d28 as this is an ink transfer mixed media piece. The underpainting is in #acrylics with the transfer from inkjet using #liquitex gloss medium. I left the transfer on for two nights then gently scrubbed it off with water this morning. Still a WIP ...
from instagram

daily snapshot: October 29, 2015 at 08:20AM

There's nothing that can't be improved with a little Charles Atlas! #acrylicpainting #mixedmedia #nudeart #liquitexpaint #winsorandnewton
from instagram

Seasons come, seasons go - a year rolls round again

https://goo.gl/photos/UexWSY55e2YVd52k7

A year ago we were picking pumpkins and walking to school.

posted from Bloggeroid

daily snapshot: October 27, 2015 at 09:08AM

studio shot Tuesday: sea of red
from instagram

One year ago

On our way!

https://goo.gl/photos/Lvsg3nS5K71wBDNP6

posted from Bloggeroid

daily snapshot: October 23, 2015 at 11:42AM

Visits from bears - last night and right outside our front door. One branch broken and berries eaten. Claw marks up the tree trunk.
from instagram

Phthalimide Conjugation: The “Black Spot” for Targeted Protein Destruction

via Accelerating Science » Amanda Maxwell http://ift.tt/1PKXfwR

“And now, shipmates, this black spot? ‘Tain’t much good now, is it?”   ― Robert Louis Stevenson, Treasure Island   Imagine being able to specifically target a cancer protein for immediate destruction, slipping Robert Louis Stevenson’s notorious black spot into a crevice in the secondary structure and spelling imminent death. Well, this is what Winter et Read the rest of this article

The post Phthalimide Conjugation: The “Black Spot” for Targeted Protein Destruction appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1Me1xxr
via IFTTT

spt22oct15: repetition

vanishing point

Don't chew with your mouth open.
One pair of shoes only.
Dirty plates in the dishwasher/sink.
Thursdays.
Dinner!
... some of my recent uttered repetitions.

... which leaves me with no energy to mention the bulb that needs replacing/minor repairs/etc/etc/etc
... and absolutely no energy to remember when/how/why/what/whatever

*also known as nagging

Placental Biobanking: The Ties that Bind

via Accelerating Science » Amanda Maxwell http://ift.tt/1MaYdmL

When researchers Fannin and Kent interviewed staff and donors involved with the “Children of the 90s” placental biobank, ALSPAC (Avon Longitudinal Study of Parents and Children), they found an ongoing narrative from staff and donors important in building and maintaining this unique research population.1 As placentas are more than just clinical waste from the birthing process, the Read the rest of this article

The post Placental Biobanking: The Ties that Bind appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1W76tIW
via IFTTT

daily snapshot: October 21, 2015 at 10:14AM

October flowers from mr ebb :)
from instagram

one year ago ... in the middle of the madness

https://goo.gl/photos/t7bJ5uUe7H5Bt16b6

Days away from moving out and moving in, then moving out and moving in again. A year ago and only now do I feel as if I'm recovering.

posted from Bloggeroid

daily snapshot: October 19, 2015 at 10:32PM

#inktober d19: #stoppedharper, and that is all
from instagram

Collaborative Proteomics Project Reveals Cancer’s Manipulation of Cell Signaling

via Accelerating Science » Amanda Maxwell http://ift.tt/1RRktkj

The publication of two papers from the Linding lab in the University of Copenhagen’s (UCPH) Biotech Resource and Innovation Centre (BRIC) heralds the first release of data resulting from collaboration with Thermo Scientific.1,2 Using Orbitrap mass spectrometry in conjunction with next generation sequencing (NGS), Creixell et al. demonstrate how genetic mutations drive cancer progression. The papers Read the rest of this article

The post Collaborative Proteomics Project Reveals Cancer’s Manipulation of Cell Signaling appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1QLxKtT
via IFTTT

daily snapshot: October 18, 2015 at 11:05PM

#inktober d18: ink sketch - normally I sketch in pencil first then ink over, but tonight's is all Pitt Artist Pen
from instagram

daily snapshot: October 16, 2015 at 10:35PM

#inktober d16: digital ink - ms griz #catsofinstagram
from instagram

daily snapshot: October 16, 2015 at 04:49PM

TGI Friday: start the week celebration with a DQ Blizzard
from instagram

spt 15oct15: keeping myself in the picture

still life with dog

This month, I'm taking part in inktober - a daily ink sketch project that I'm playing along with on Instagram. It's an inspiring hashtag to take part in - lots of encouragement and inspiration, though the "pressure" of producing an inked piece every day can be a bit overwhelming. It's difficult to know what to draw.
So this year I thought I might try inking up some of my social media postings, looking through Instagram for self portraits from my spt (self portrait thursday) posts.
Hmmm - I haven't taken many recently.
I don't seem to be taking that weekly snapshot and telling all about what's going on in my head.
Why not? I have no idea.
There is still a lot of stuff going on in my head.
Did you miss me?
Or maybe I should post more pics of Rosco ... what do you think?

Quick and Simple Protocol for Assaying Perfluoroalkyl Contamination in Foods

via Accelerating Science » Amanda Maxwell http://ift.tt/1jpWA82

Perfluoroalkyls (PFAs), commonly used as surface treatment agents in a number of routine applications including polymerization, outdoor clothing and in firefighting foams, are environmental contaminants that find their way into the food chain. Unfortunately, these compounds have a long half-life and are not broken down in the body for excretion1. The effect they have on Read the rest of this article

The post Quick and Simple Protocol for Assaying Perfluoroalkyl Contamination in Foods appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1NIGGlS
via IFTTT

Celebrating Frances Oldham Kelsey for Ada Lovelace Day

Every year, Ada Lovelace Day rolls around, reminding the world that yes, we do need to reach out in support of women in STEM (science, technology, engineering, mathematics). To defend this assertion, this year I’m only putting forward two pieces of evidence:  ....

Read more here: http://www.talksciencetome.com/celebrating-frances-oldham-kelsey-ada-lovelace-day/

 

daily snapshot: October 12, 2015 at 09:30PM

#inktober d12: Rosco plays model (again) #rescuedog #bcspcaalumni #dogsofinstagram #copic
from instagram

daily snapshot: October 08, 2015 at 09:36PM

#inktober d8: peek-a-boo #copic #spt
from instagram

SureTect PCR for Production Environment Salmonella Monitoring

via Accelerating Science » Amanda Maxwell http://ift.tt/1Zf9l5L

Salmonella species are a major cause of foodborne infection. Food producers have therefore developed stringent control measures to prevent Salmonella contamination by monitoring for this pathogen wherever food is handled during processing, including on the production line. In order to improve food safety, producers monitor for compliance with hygiene standards, but for this control to Read the rest of this article

The post SureTect PCR for Production Environment Salmonella Monitoring appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1JUoCxf
via IFTTT

Designing Safe Mimics for Ebola Virus Research

via Accelerating Science » Amanda Maxwell http://ift.tt/1L0euUC

Clinton et al. (2014) recently published a paper outlining the use of mimics as an elegant solution to researcher safety while working with a deadly pathogen.1 Ebola virus (EBOV) infection causes a devastating hemorrhagic disease in humans, with almost 60% fatality in most outbreaks where medical care is limited.  In order to research novel therapeutics and investigate Read the rest of this article

The post Designing Safe Mimics for Ebola Virus Research appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1GnN4XL
via IFTTT

daily snapshot: October 01, 2015 at 11:04PM

#inktober day 1: think before you pink #spt
from instagram