daily snapshot: December 31, 2015 at 11:21PM

SPT31dec15: happy new year from us to you
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daily snapshot: December 31, 2015 at 10:08PM

At this point my nose was so cold I couldn't tell if it was dripping or not
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daily snapshot: December 31, 2015 at 07:52PM

Jellies!
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daily snapshot: December 31, 2015 at 07:20PM

Happy new year's eve from Vancouver
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daily snapshot: December 31, 2015 at 07:17PM

Spending new years eve @ festival of lights @vandusen
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daily snapshot: December 30, 2015 at 08:38AM

My #2015bestnine -ask from #inktober :)
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Biobank Donors as Active Participants: A New Biobanking Model

via Accelerating Science » Amanda Maxwell http://ift.tt/1JGINQN

Most of the literature on dealing with biobank donors centers on the ethics of collecting, storing and using samples. Informed consent, re-consent, anonymization and disclosure of results are all hot topics, with local and national organizations spending considerable effort on ensuring that biobank management pays proper care and attention to donor treatment. Furthermore, the role Read the rest of this article

The post Biobank Donors as Active Participants: A New Biobanking Model appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1VnA5O0
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daily snapshot: December 28, 2015 at 05:44PM

Exploring new worlds #bloedel
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daily snapshot: December 25, 2015 at 10:33PM

The Christmas sweater on a reluctant model #tripawd #christmasasithappens
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daily snapshot: December 25, 2015 at 09:57PM

the cute alabaster piggy from @blackberryarts is mine #christmasasithappens
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daily snapshot: December 25, 2015 at 09:41PM

Reading matters #christmasasithappens
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daily snapshot: December 25, 2015 at 09:39PM

New hat! from @wildcraftedwool :) #christmasasithappens #christmas2015
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daily snapshot: December 25, 2015 at 09:34PM

all the fun of the unwrap ... at 9:30pm (it was hell getting away from Cypress after snowboarding) #christmasasithappens #christmas2015
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daily snapshot: December 25, 2015 at 09:28PM

#christmasasithappens #christmas2015 slippers!
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daily snapshot: December 25, 2015 at 09:18PM

the daily pussy: under the influence (new catnip toy) #christmasasithappens
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daily snapshot: December 25, 2015 at 03:47PM

Ho Ho Ho on Cypress this afternoon #christmasasithappens
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daily snapshot: December 25, 2015 at 03:46PM

Merry Christmas - the gang's all here #christmasasithappens
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daily snapshot: December 25, 2015 at 03:43PM

A very merry Christmas: up, up and away #christmasasithappens #christmas2015
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daily snapshot: December 25, 2015 at 03:40PM

The bus #christmasasithappens #christmas2015
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daily snapshot: December 25, 2015 at 03:38PM

Merry Christmas on snow. Turkey thawing back home while we're out sliding
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daily snapshot: December 25, 2015 at 10:06AM

Christmas scritch
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daily snapshot: December 25, 2015 at 10:04AM

the daily pussy: Christmas kitten
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daily snapshot: December 25, 2015 at 08:36AM

Merry Christmas #christmas2015 #christmasasithappens
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Novel Myoblast Differentiation/Fusion Model Defined by Quantitative Proteomics

via Accelerating Science » Amanda Maxwell http://ift.tt/1Th90eg

Muscle tissue growth and repair during life takes place through the actions of satellite cells. Given the right signals, these stem cells proliferate and differentiate into myoblasts. Once differentiated, the new myoblasts fuse to each other and also with existing myofibers, thus forming the multi-nucleate cell scaffold characteristic of functioning muscle tissue. Gardner and co-authors Read the rest of this article

The post Novel Myoblast Differentiation/Fusion Model Defined by Quantitative Proteomics appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1O9gy2s
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daily snapshot: December 22, 2015 at 06:20PM

Man and boy: night skiing family style on Cypress
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The Million Veteran Program: Biobanking to the Max

via Accelerating Science » Amanda Maxwell http://ift.tt/1mxI4fE

With a target of one million recruitments, the United States Million Veteran Program (MVP) is already gathering an impressive data collection.1 Since the program started in 2011, numbers recruited in August 2015 stood at 397,014 veterans recruited from over 3 million invited. With two ongoing studies and four more in the approval stages, this observational cohort Read the rest of this article

The post The Million Veteran Program: Biobanking to the Max appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1mxIhj6
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Combining Phosphoproteomics with Exome NGS to Understand Cancer

via Accelerating Science » Amanda Maxwell http://ift.tt/1S6kEKB

Recent publications from the Linding lab in the University of Copenhagen’s (UCPH) Biotech Resource and Innovation Centre (BRIC) have shown a more extensive disruption of cell signaling pathways by cancer mutations than previously expected. Criexell et al. (2015) used a quantitative mass spectrometric-based phosphoproteomics approach in combination with exome next generation sequencing (NGS) to identify Read the rest of this article

The post Combining Phosphoproteomics with Exome NGS to Understand Cancer appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1JpXkAe
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2015 science gifts guide for Talk Science to Me

Dino Pet by BioPop from BioPop on Vimeo.

Hoping this reaches you in good time for some seasonal gifting (or hinting), here’s the Talk Science to Me 2015 list of suggestions for the scientist (or science lover) in your life.

I wrote this! Read more at
http://www.talksciencetome.com/tis-season-2015-cool-science-gifts-edition/

Rising to the Information Technology Challenge in Biobanking

via Accelerating Science » Amanda Maxwell http://ift.tt/1lSzF6G

Gone are the days when biobanks were single, stand-alone collections, comprising nothing more than tissue specimens. Modern biobanks frequently belong to a network of similar biorepositories with interconnected data streams to facilitate research access and sharing. Quinlan et al. (2015) reviewed some of the informatics challenges associated with setting up an interconnected biobanking network, describing Read the rest of this article

The post Rising to the Information Technology Challenge in Biobanking appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1OafNIi
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daily snapshot: December 16, 2015 at 03:22PM

This month's stunning bouquet from @johnfoord via @portmoodyflowers :)
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daily snapshot: December 15, 2015 at 10:55AM

In all her glory - the Madonna of domestic chaos (unfinished) #oilpainting #artist #oils #spt
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Life with Dog: The Dog Patch Kennels and Daycare

Dog owners all know that day-to-day life is much better with a four-legged friend, although there are some things that make it easier. In February this year, I pulled together a list of dog daycares and boarding kennels in the Tri Cities to help owners. Smart move, as by April we had a dog once again and by late June, were looking for boarding kennels for a last-minute summer holiday.

Read more on The V3H here http://thev3h.com/2015/12/life-with-dog-the-dog-patch-kennels-and-daycare/

The Dog Patch
645 Laurier Ave, Port Coquitlam | 604.942.1166 | www.thedogpatch.ca


from Amanda Maxwell – The V3H.com – Port Moody, Coquitlam, Port Coquitlam http://ift.tt/1SZPRNK
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sunday sunday

My other dining companion, on his device #inkredible #digitalsketch

A photo posted by pomomama (@ebbandflo) on Dec 13, 2015 at 4:23pm PST

Weekends are for family ... and catching up on the workload hours that somehow slip by during the week.

This has been my first year of almost full-time employment/self employment. It's been amazing but at the same time, tiring. Right now, I am fully fed up with having to track every single minute and hour to make sure I'm doing something "productive". It is exhausting and I'm feeling quite burned out by it all.

There are enough hours in the week for me to fulfil my contract commitments. However, add this to my domestic hours and parenting hours and volunteer hours, and it gets a little crazy. Once again I'm at the limit and this time I cannot see what more I can cut out of my life.

OK I could cut back on the paid work, but after all I've worked for this just doesn't seem sensible. Also, I'm enjoying it - it's different, valued, makes my brain spin the cogs, it makes a difference ...
I could cut back on the domestic stuff ... but who would do it instead? The stuff just doesn't magically disappear. I may just have to make it so that there is less domestic stuff to do - maybe laundry could be a personal responsibility, fewer meals cooked, fewer domestic arrangements made, operate the house more as a roomshare with individual responsibilities?

We also need more house renovations, domestic management and ongoing facilities maintenance - it's not enough to live in a place, it also has to be a home at least to me.

Since last year's moving project management, I've been doing less of the domestic facilitation anyway and nothing serious has happened - it's just that less now happens because I'm not making it happen in the first place. With me?

I'm not about to cut back on the parenting hours, though after school activities do take care of a major amount of time these days :)

And I cannot afford to cut back on looking after myself. I desperately need the exercise, friends, relationship and creative time.
Looking after myself with exercise, creative projects, keeping up with friends, and so on has once again slipped by me this year. I've had a once-a-week art class as my only enforced creative time. Friends - pfft! there has been precious little time for them. Exercise - again, no time. Work, domestic and parenting has been all consuming.

I'm not sure how, but this all has to change in 2016.

daily snapshot: December 10, 2015 at 12:37PM

spt 10dec15: outdoor living - getting into a racing tuck is easier into the wind
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Snip Snip! CRISPR-Cas9 Genomic Editing Characterizes the Prion Protein Knockout Proteome

via Accelerating Science » Amanda Maxwell http://ift.tt/1ltYPbs

Although prion proteins are widely implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimer’s in animals and humans, their normal physiological function is still relatively unknown. However, Mehrabian et al. (2014) recently published a cell-specific deep proteome analysis that gives the first clues into prion protein function. Using CRISPR-Cas9 technology, the researchers created knockout Read the rest of this article

The post Snip Snip! CRISPR-Cas9 Genomic Editing Characterizes the Prion Protein Knockout Proteome appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1IUqYx6
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Pallet to Palate: Extending Shelf Life and Safety in Microgreens with PCR

via Accelerating Science » Amanda Maxwell http://ift.tt/1lLlZtq

For producers of perishables with limited shelf life, shaving even a few days from on-site food safety procedures and getting the product into the hands of customers faster is a valuable goal. And that’s exactly what Florida Urban Organics has done by implementing real-time PCR into their pathogen screening workflow. Florida Urban Organics is an innovative, certified Read the rest of this article

The post Pallet to Palate: Extending Shelf Life and Safety in Microgreens with PCR appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1RBNodY
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daily snapshot: December 07, 2015 at 09:06AM

Pulling a face: not as happy with this one. Used #oilbars directly on the gesso'ed paper then spread and mixed the colours with the knife. I think it's way too muddy
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Preventing Foodborne Staphylococcal Disease – Hygiene Matters!

via Accelerating Science » Amanda Maxwell http://ift.tt/1TyrdUS

Although meat products are an important source of foodborne disease caused by Staphylococcus aureus, Kadariya et al. (2014) note that other foodstuffs such as sandwich fillings, bakery goods, salad items and dairy can also transmit this microbe. Since contamination mostly arises opportunistically from improper handling practices in the retail food chain, producers can take steps Read the rest of this article

The post Preventing Foodborne Staphylococcal Disease – Hygiene Matters! appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1YK2tMy
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daily snapshot: December 02, 2015 at 10:14AM

The Daily Dog: All-terrain #tripawd - Rosco tries out his harness #rescuedog
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Real-Time Peptide Sequencing with Novor

via Accelerating Science » Amanda Maxwell http://ift.tt/1Nq91vZ

A new proteomics data analysis tool, Novor, describes peptide sequencing in real time, delivering results as the spectra roll out of the mass spectrometer. As Bin Ma’s recent paper (2015) reveals, Novor’s real-time sequencing ability could also integrate well with instrument control programs.1 Although real-time sequencing capabilities exist for several genomics strategies, this tool has Read the rest of this article

The post Real-Time Peptide Sequencing with Novor appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1LNI67U
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Understanding Microbial Biofilms for Seafood Safety

via Accelerating Science » Amanda Maxwell http://ift.tt/1NZTjUw

Food industry operators dealing with seafood must understand the importance of microbial biofilms and their impact on food safety. Mizan et al. (2015) recently published a comprehensive review on biofilms and seafood production, discussing the epidemiology of the main foodborne pathogens affecting these products. In addition to reviewing this important microbial feature, they also looked Read the rest of this article

The post Understanding Microbial Biofilms for Seafood Safety appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1NZTm2x
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Deep Mining the Triple-Negative Breast Cancer Proteome for Therapeutic Hope

via Accelerating Science » Amanda Maxwell http://ift.tt/1NDseMB

From a label-free deep dive into the triple-negative breast cancer (TNBC) proteome, Lawrence et al. (2015) have uncovered some potential targets for therapeutic investigation.1 Using 24 cancer samples (cell lines and biopsy tissues), the research team combined a proteomics analysis approach with drug sensitivity testing and integration of genomics data. The methodology and resulting data allowed Read the rest of this article

The post Deep Mining the Triple-Negative Breast Cancer Proteome for Therapeutic Hope appeared first on Accelerating Science.

from Accelerating Science » Amanda Maxwell http://ift.tt/1lpBhUq
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