In 25 to 35% of cases of primary infertility, doctors cannot reach a diagnosis that fully explains why a patient is infertile. This means that many women never learn why they cannot conceive and, as a result, fail to receive effective treatment. Manohar et al. (2015) attempt to set fertility research on the right track Read the rest of this article
The post The Endometrial Proteome and Unexplained Infertility appeared first on Accelerating Science.
Giffen et al. (2015) demonstrate that promotion, enabling access to biosamples and data, and widening the audience of interest all enhance the value of a historical biobank collection.1 Describing the National Heart, Lung, and Blood Institute (NHLBI) Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) initiative, the authors explain the steps taken to consolidate the Read the rest of this article
The post Promoting Access Increases Historical Biobank Value appeared first on Accelerating Science.
The single biggest asset in biobanking is data—this is what makes a bioresource so valuable to the research world. But it is also potentially the biggest headache. In order to realize its full potential, a biobank must make data available to researchers, which then can jeopardize its biggest stakeholders: the donors. Releasing data is a Read the rest of this article
The post The Biobanking Data Tease: Reveal Too Much or Too Little? appeared first on Accelerating Science.
Plant antimicrobial peptides, or PAMPs, are protein compounds produced by plants to defend against microbial attack1. They are positively charged, amphiphilic molecules found throughout the plant, existing in leaves, stem, stalk and other tissues. Plants release PAMPs in response to microbial infection and infestation, or produce them constitutively as part of the overall pathogen defense Read the rest of this article
The post Plant Antimicrobials and the Food Industry: Part 2 – Antimicrobial Peptides appeared first on Accelerating Science.
With a goal of collecting multiple biosamples, researchers in the GTEx (Genotype-Tissue Expression) project faced a problem: where to get samples for a reference library cataloging non-diseased tissue gene expression. Carithers et al. (2015) provide an overview of the resourceful solution to this potentially limiting factor in study design.1 The GTEx project aims to examine the correlation Read the rest of this article
The post Bring out Your Dead: The GTEx Study and Cadaver Tissue Procurement appeared first on Accelerating Science.
Mass spectrometry–based proteomics research generates vast amounts of digital data, from both the initial spectral outputs to the peptide and the protein identifications that emerge from them. Recent analysis apps added to the Thermo Fisher Cloud service can help researchers take the next steps in interpreting results, looking more closely to interpret the data and Read the rest of this article
The post Head in the Thermo Fisher Cloud for Proteomics Data Analysis appeared first on Accelerating Science.
In order to maintain product quality and protect consumers, food producers must control microbial contamination that could cause spoilage or foodborne illness. However, current expectations from consumers mean that natural is better for acceptance in the marketplace. For this reason, food industry researchers are looking at plant antimicrobials as ‘natural’ tools to control bacteria, viruses, Read the rest of this article
The post Plant Antimicrobials and the Food Industry: Part 1 appeared first on Accelerating Science.
Structurally speaking, all proteins have a beginning and an end, and proteomically speaking, the study of each end has its own –omic. Tanco et al. (2015) provide a handy review of C-terminomics, the study of modifications that impact the protein’s C-terminus.1 The C-terminal tail of a protein plays an important role in regulating activity and Read the rest of this article
The post C-Terminomics: What’s Happening at the End of the Rainbow appeared first on Accelerating Science.
To consumers of fresh produce and allied foodstuffs, green spells fresh and premium. This is why unscrupulous food producers are occasionally tempted to boost their products with banned additives. Fang et al. (2015) show how regulatory officials can monitor suspiciously green food oils using ultra-high performance liquid chromatography (UHPLC) coupled with either high resolution mass Read the rest of this article
The post Green Dye in Food Oil – No Thanks! appeared first on Accelerating Science.
Mass spectrometric–based proteomics analysis generates large amounts of digital data from spectral displays. Researchers are increasingly making these data available to other scientists by uploading the files to public repositories using tools such as ProteomeXChange. For optimal utilization that maximizes the value of these resources, researchers must be able to easily interrogate and visualize the Read the rest of this article
The post Proteomics Data Visualization and Comparison with MS-Viewer appeared first on Accelerating Science.
Biobanking has an important role to play in discovering the molecular basis of disease. Researchers need access to representative libraries of biospecimens, and these samples need to be preserved in excellent quality for valid genomic investigation. Lee et al. (2015) took a closer look at biobanking ileum mucosa samples for genomic studies, paying close attention Read the rest of this article
The post Harvesting Ileum Mucosa Tissue: Effect of Ischemia on RNA Stability appeared first on Accelerating Science.
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